Health information

Alcohol use increases cancer risk - scientists

Each of us has heard a lot about the harmful effects of alcohol. But how exactly does ethyl alcohol destroy our body? In the process of metabolism of ethanol, acetaldehyde is formed - a toxin that provokes double-stranded breaks in DNA.

Scientists have continued research in this area and found that blood-forming cells are the first to suffer - it is their DNA that is most often attacked by an aggressive toxin. As a result, the likelihood of developing cancer increases significantly. The research results were published in the authoritative edition of Nature.

How was the research done? The process of the destructive effect of ethanol on the DNA of stem cells was monitored in mice. It turned out that each succeeding generation suffers more. That is, from the generation of parents whose body is poisoned by the decay products of ethanol, the offspring will be born with DNA defects. And the organism of representatives of the new generation no longer has the ability to break down and remove acetaldehydes.

For example, the body of a healthy person has the ability to self-purify from acetaldehydes - first, enzymes are produced that break down the product into easily excreted components. Secondly, the regeneration of damaged DNA chains is immediately activated. That is, if the body rarely suffers from poisoning by decay products of ethanol, it has time to recover.

But alcohol abuse leads to the fact that each subsequent generation will have less ability to self-recovery of the body. Thus, after a few decades, a race of people with congenital mutations that affect the body's defenses may appear on Earth. This will cause a rapid increase in the number of cancer diagnostics, in particular - esophageal cancer.

Watch the video: Drinking too much alcohol can increase cancer risk (December 2019).